Ten-year-old Wille has always dreamed of becoming a superhero and fighting crime alongside his police-hero dad a dream which is shattered when his new baby brother Charlie is born with actual superpowers.

When evil wizards Razamel and Gargamel take Papa Smurf, the Smurfs embark on a mission to the real world to save him. With help from some new friends, they must discover what defines their destiny to save the universe.