Nicholas (O' Shea) and Isabel (Skelly) are made for each other, but fate does not always choose the easiest path to true love. As destiny pulls them together, so do family, passion, and faith drive them apart.

Ethan Hunt and the IMF team continue their search for the terrifying AI known as the Entity - which has infiltrated intelligence networks all over the globe - with the world's governments and a mysterious ghost from Ethan's past on their trail.